Hawthorn Leaf Extract

Hawthorn Leaf Extract is extracted from the dried leaves of Hawthorn, and the main active ingredients are flavonoids. Hawthorn leaf flavonoids (HLF) have various pharmacological effects and are widely used in healthcare products and clinical medicine.

It can promote vasodilation, increase coronary blood flow, lower blood pressure and lipids, and increase cardiac blood flow to the human body.

Hawthorn leaves are the red leaves of the genus Hawthorn in the Rosaceae family. It has a long history of medicinal use in China. The 2005 edition of "Chinese Pharmacopoeia" officially included hawthorn leaf extract powder, its main chemical component is total flavonoids.

Flavonoids widely exist in plants in nature and are secondary metabolites of plants. They have antibacterial, anti-inflammatory, heat-clearing, detoxifying, soothing, and diuretic effects. They are scavengers of most oxygen-free radicals and have significant therapeutic effects on coronary heart disease and angina pectoris. Now, they are getting more and more people's attention.

1. Antioxidant effect. The total flavonoids of Hawthorn Leaf Extract can reduce the content of MDA in cardiomyocytes, and increase the activity of SOD and NO content in cells, thereby reducing the degree of arrhythmia in cardiomyocytes after ischemia and hypoxia injury, and delaying cardiac arrest. It also has a good protective effect on ischemia-reperfusion of brain tissue and kidney tissue. Studies have shown that the total flavonoids of hawthorn can significantly resist the damage caused by free radicals, inhibit the morphological changes of apoptosis, and improve the activity of neurons.

2. Anti-atherosclerosis. The total flavonoids of hawthorn leaves can dilate coronary blood vessels, increase coronary blood flow and coronary sinus blood oxygen content, improve heart blood supply, and regulate and improve the cardiovascular system.

3. Hypoglycemic effect. The total flavonoids of hawthorn leaves can significantly reduce blood sugar levels, improve dyslipidemia, reduce blood lipids and reduce the formation of lipid peroxidation, reduce the accumulation of fat in the liver caused by diabetes, especially significantly reduce fructosamine and sorbitol levels.

4. Anti-platelet aggregation effect. HLF can reduce the amount of fibrinogen, reduce whole blood specific viscosity, plasma specific viscosity, and serum specific viscosity, and reduce RBC aggregation index and RBC volume. The experimental results show that the total flavonoids of hawthorn can improve the blood stasis state.