
Ergothioneine Powder
No Additives or Fillers
100% Natural, Non-GMO, Non-ETO, Non-Allergenic
Premium quality, Competitive price, and Excellent Service
Excellent Water Solubility, Stability, and Fluidity
CAS No.: 497-30-3
Specification: NLT 99%
Appearance: White crystalline powder
Test Method: HPLC
Package: 25kg/drum
Lead time: 7 days after payment
Delivery: FedEx, DHL, Ship by air, Ship by sea
Storage: Store in the original tightly closed package from moisture and sunlight
Certificate: ISO, Kosher, Halal, FDA, FSMA
MOQ: 1kg
your selected ergothioneine 99% Powder supplier
Ergothioneine Powder is a premium ingredient for innovative cosmetic formulations and science-backed dietary supplements due to its natural, mushroom-derived origin, proven stability, and multiple health benefits. Unlike synthetic antioxidants, our ergothioneine 99% powder is sourced from edible porcini mushrooms (Boletus Edulis). It is produced through carefully controlled extraction and purification processes, guaranteeing high purity without synthetic additives. Due to its natural origin, our powder is efficiently absorbed and retained in human tissues, particularly in cells exposed to high oxidative stress (e.g., skin, liver, and eyes). Unlike some antioxidants that degrade easily, L-ergothioneine 99% powder remains stable under heat, light, and certain pH levels, making it ideal for formulations in supplements, cosmetics, and functional foods. The powder's optimal particle size ensures excellent fluidity, facilitating easy handling and incorporation into various product formulations.
In 2017, the European Union approved ergothioneine as a Novel Food, confirming its safety for human consumption. Since humans and animals cannot synthesize ergothioneine internally, it must be obtained through diet (e.g., mushrooms, black beans, oats) or supplementation. Ergothioneine's ability to neutralize free radicals, reduce UV-induced damage, and support collagen production makes it a sought-after ingredient in anti-aging serums, creams, and sun care products. Research suggests ergothioneine may support cognitive function, reduce inflammation, and protect against age-related cellular damage, driving demand in nutraceuticals and wellness supplements.
Inhealth Nature enjoys long-term and stable relationships with our clients because we focus on customer service and providing high-quality herbal extracts. If you are interested in our products, we can tailor them to cater to your specific product needs and market demands, and our short lead time on orders guarantees you'll get our ingredients on time.


Your Selected and Reliable Partner in Natural Ingredients
Tell us your product goals, we'll customize the perfect botanical solutions and formulations to enhance your brand value and bring about multiple business potentials.
ergothioneine safety and regulations
Ergothioneine is widely regarded as safe by major international regulatory bodies, including the FDA, EFSA, and Health Canada. Its approval in food, supplements, and cosmetics is supported by extensive safety data.
Safety Profile of Ergothioneine
A. Generally Recognized as Safe (GRAS)
a. In the United States, ergothioneine has achieved GRAS (Generally Recognized as Safe) status for use in food and beverages.
b. The FDA has reviewed scientific data and concluded that ergothioneine is safe at specified levels (typically up to 30 mg per day in supplements.
B. Toxicological Studies
a. Multiple animal and human studies have shown no adverse effects at typical consumption levels.
b. Ergothioneine has low toxicity, with no evidence of mutagenicity, carcinogenicity, or reproductive harm.
c. The European Food Safety Authority (EFSA) has also evaluated ergothioneine and found it safe for consumption.
International Regulatory Status
A. United States (FDA)
a. Approved as a dietary ingredient under GRAS.
b. Permitted in foods, beverages, and supplements within specified limits.
B. European Union (EFSA & Novel Food Regulations)
a. Ergothioneine is classified as a Novel Food.
b. Approved for use in food supplements and functional foods after safety assessment.
C. Japan (FOSHU & FFC)
a. Recognized as a Functional Food Component (FFC) under Japan's Food for Specified Health Uses (FOSHU) system.
b. Approved for anti-aging and antioxidant health claims.
D. Canada (Health Canada)
a. Permitted as a Natural Health Product (NHP) when used in approved supplement formulations.
E. Australia & New Zealand (FSANZ)
a. Listed as an approved novel food ingredient with specified maximum levels in supplements.
specification sheet
|
Item |
Specification |
Result |
Test Method |
|
Purity |
≥99% |
99.95% |
HPLC |
|
Appearance |
White Crystalline Powder |
Conforms |
Visual |
|
Odor |
No Distinct Odor |
Conforms |
Organoleptic |
|
Particle Size |
98% pass through 100 mesh |
Conforms |
Sieve |
|
Bulk Density |
0.45g/mL- 0.65 g/mL |
0.50g/mL |
Bulk Density Meter |
|
Loss on Drying |
≤ 0.5% |
0.15% |
TGA |
|
Arsenic (As) |
≤ 2 ppm |
<1 ppm |
ICP-MS |
|
Cadmium (Cd) |
≤ 2 ppm |
<0.5 ppm |
ICP-MS |
|
Mercury (Hg) |
≤ 1 ppm |
<0.1 ppm |
ICP-MS |
|
Lead (Pb) |
≤ 3 ppm |
<1 ppm |
ICP-MS |
|
Total plate count |
≤1000cfu/g |
Conforms |
USP<61> |
|
Yeast & mold |
≤100cfu/g |
Conforms |
USP<61> |
|
E. Coli |
Not detected |
Conforms |
USP<62> |
|
Salmonella |
Not detected |
Conforms |
USP<62> |
|
Staphylococcus aureus |
Not detected |
Conforms |
USP<62> |

superb health benefits
Ergothioneine Powder has gained attention for its potential health benefits, particularly in anti-aging, neuroprotection, and cellular health. Below is a detailed summary of its key benefits based on research findings:
Powerful Antioxidant Protection
L-ergothioneine 99% powder acts as a cellular shield against oxidative stress, neutralizing harmful free radicals that contribute to aging and chronic diseases. Unlike other antioxidants, it is highly stable and does not degrade easily, making it particularly effective in protecting long-lived cells (e.g., neurons, retinal cells, and stem cells).
a. Comparison: Some studies suggest it may be up to 3,000 times more potent than vitamin E in antioxidant activity and 6 times that of glutathione.
b. Retention: Unlike short-lived antioxidants (e.g., quercetin), ergothioneine accumulates in tissues and remains active for weeks.
Supports Brain Health and Cognitive Function
Low ergothioneine levels are linked to neurodegenerative diseases like Alzheimer's and Parkinson's. Research highlights its ability to:
a. Cross the blood-brain barrier, protecting neurons from oxidative damage.
b. Improve memory and executive function in aging populations.
c. Reduce markers of brain shrinkage and vascular damage in dementia patients.
Anti-Aging and Cellular Longevity
Ergothioneine 99% powder is dubbed a "longevity vitamin" due to its role in:
a. Telomere protection: Slows telomere shortening, a key marker of cellular aging.
b. Senescence reduction: Eliminates aged (senescent) cells that contribute to tissue degeneration.
c. Skin health: Clinical trials show reductions in wrinkles, UV spots, and improved skin elasticity with supplementation.
Heart and Vascular Health
Higher blood levels of ergothioneine correlate with reduced cardiovascular disease risk:
a. Improving endothelial function and reducing arterial stiffness.
b. Lowering inflammation and oxidative stress in blood vessels.
Liver and Kidney Protection
a. Liver: Reduces fat accumulation and inflammation in metabolic liver disease (MASLD) by enhancing autophagy.
b. Kidneys: Protects against oxidative damage and kidney stone formation.
Immune System Support
a. Enhances immune cell function (e.g., monocytes and macrophages).
b. Reduces pro-inflammatory cytokines like IL-8, potentially aiding in chronic inflammation management.

our certificates
As an experienced and skilled manufacturer and supplier, we pledge to produce and offer our global customers superior herbal extracts (powder, oil, liquid, etc.) that are safe and have a high bioavailability. Due to our several international certifications, including ISO, FSSC, FDA, Kosher, Halal, FSMA, and others, we can ensure that the final herbal extracts we sell adhere to strict standards and regulations regarding potency, quality, and purity.
Because of our complete compliance with the aforementioned international certifications, our clients worldwide can be certain of the safety, effectiveness, and high bioavailability of the herbal extracts we offer. When clients seek to collaborate with an outstanding and dependable provider of premium herbal extracts, our commitment to the aforementioned certifications offers them peace of mind.

our factory
a. We are a leading herbal extract manufacturer with more than 11 years of industry experience.
b. We have over 300 products for you to choose from, including monomers, standardized extracts, plant powders, essential oils, supercritical CO2 extracts, fermented nutrients, and food additives.
c. We have a clean workshop and cutting-edge equipment as per GMP standards.
d. We have sophisticated and experienced R&D and service teams to support you.




inhealth nature supports
★ Sample Support: free samples for your testing before placing your orders.
★ Service Support: 7*24 after-sales service for you.
★ Shipment Support: on-hand inventory and can be delivered within 2~3 working days after payment.
★ Freight Support: FedEx, DHL, UPS, and Top Forwarder
★ Document Support: Technical Data Sheet, Certificate of Analysis, MSDS, Certificate of Origin, and so on.
our packaging

our shipping method
|
By Express |
By Air Transportation |
By Sea Transportation |
|
Suitable for less than 50kg |
Suitable for more than 50kg |
Suitable for more than 500kg |
|
Fast: 3-7 days |
Fast: 3-7 days |
Slow: 7-45 days |
|
High cost |
High cost |
Low cost |
|
Door-to-door service |
Port-to-port service |
Port-to-port service |
|
Easy to pick up the goods |
Professional broker needed |
Professional broker needed |

ergothioneine applications
Here's a detailed description of Ergothioneine Powder's product applications across cosmetics, dietary supplements, functional foods, and food additives, based on industry usage and formulations:
Cosmetics
Ergothioneine is widely incorporated into skincare and cosmetic formulations due to its stability and multifunctional properties:
a. Anti-aging creams/serums: Used for its antioxidant properties to protect skin from oxidative stress and environmental damage.
b. Sunscreens/UV protectors: Acts as a natural UV filter, mitigating photodamage.
c. Brightening products: Inhibits melanin production to address hyperpigmentation.
d. Barrier-enhancing formulations: Strengthens the skin's lipid barrier to reduce sensitivity.
e. Water-soluble additives: Easily blended into toners, essences, and lotions.
Dietary Supplements
Ergothioneine is formulated into supplements for its bioavailability and stability:
a. Capsules/tablets: Often combined with other antioxidants or vitamins.
b. Powder blends: Mixed into protein shakes or wellness powders.
c. Specialty supplements: Targeted for aging support or cellular health.
Functional Foods & Beverages
Approved as a novel food ingredient in the EU and GRAS in the U.S., ergothioneine is added to:
a. Fortified beverages: Energy drinks, herbal teas, and dairy alternatives.
b. Snack bars: Cereal bars or protein bars for added functional benefits.
c. Confectionery: Gummies or chews with health claims.
Food Additives
Primarily used for preservation and quality enhancement:
a. Meat/seafood preservative: Extends shelf life by reducing oxidation and discoloration.
b. Wine/fermented foods: Stabilizes flavor and color by scavenging free radicals.
c. Bakery products: Incorporated into dough to improve freshness.
you can find us here
Inhealth Nature has been focused on the R&D and production of ergothioneine 99% powder for more than 11 years since 2014. Are you looking for any solutions for your products? Welcome to contact us.
Our address
802, B2, Jingye Building, Jinye Road, Xi'an, 710065, China
Phone Number
+86-18202932679

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