Oleanolic Acid Powder

Oleanolic Acid Powder

Specification: Oleanolic Acid 40% 45% 98%
Botanical Resource: Hemsleya root
Test Method: HPLC / Titration
CAS No.: 508-02-1
Appearance: Brown-yellow to off-white powder
Package: 10kg/drum or 25kg/drum
Lead Time: 2~5 days after payment received
Certificates: FSSC22000, ISO22000, Kosher, Halal
MOQ: 1kg
Advantage: Unique herbal resource, higher yield, higher purity, and better price

Shaanxi Inhealth Nature Industry Co., Ltd. is one of the most experienced manufacturers and suppliers of oleanolic acid powder in China, featured by quality products and good price. Welcome to wholesale bulk high-grade oleanolic acid powder from our factory. Contact us for free sample.

 

how much do you know about oleanolic acid?

Oleanolic Acid Powder, derived from various plant sources, possesses valuable characteristics and health benefits that contribute to its growing market presence. Oleanolic acid is characterized by its triterpenoid structure, which imparts several beneficial properties. It is known for its anti-inflammatory, antioxidant, and hepatoprotective properties, making it a valuable compound for promoting overall health and well-being. Oleanolic acid extract powder is sparingly soluble in water, but it can dissolve in various organic solvents, making it suitable for formulation in dietary supplements, skincare products, and pharmaceutical preparations. The solubility profile of this powder enables its incorporation into diverse product formulations, expanding its potential applications. Oleanolic acid is associated with a range of health benefits, making it an attractive ingredient for health-conscious consumers. It has been studied for its potential to support liver health, reduce inflammation, and exhibit antioxidant properties. Furthermore, oleanolic acid is being researched for its role in promoting cardiovascular health and managing metabolic conditions, contributing to its growing popularity in the health and wellness sector. As research continues to uncover its potential benefits, the demand for oleanolic acid extract powder is expected to persist and expand, offering promising opportunities for innovation and development in the health and wellness market. Our oleanolic acid extracts are available in different specifications, such as oleanolic acid 40%, 45%, 50%, 95%, and 98%. The purity is higher, and the color is lighter.

 

Oleanolic Acid Powder

Figure 1-Mass Spectrum of Oleanolic Acid

 

Fig.1 Mass Spectrum of Oleanolic Acid

 

botanical resource advantage

Oleanolic acid extract powder is a natural compound that can be extracted from various plants, including Hemsleya root and Glossy Privet Fruit. In this part, we will focus on the advantages of OA powder extracted from Hemsleya root compared to Glossy Privet Fruit.

One advantage of extracting OA powder from Hemsleya root is the additional bioactive compounds that it contains. Hemsleya root has been found to contain other compounds that work synergistically with oleanolic acid, enhancing its overall therapeutic effects. These additional compounds may contribute to its antioxidant and anti-inflammatory properties, providing added health benefits. In contrast, Glossy Privet Fruit primarily contains oleanolic acid and lacks these additional bioactive compounds.

Another advantage of extracting OA powder from Hemsleya root is the potential for higher purity levels and concentrations. The extraction process for Hemsleya root may yield a purer form of OA powder compared to Glossy Privet Fruit due to differences in plant anatomy and chemical composition. This higher purity level may be desirable for applications that require a more concentrated dose of oleanolic acid.

Furthermore, the geographical distribution and availability of Hemsleya root may provide advantages over Glossy Privet Fruit. Hemsleya root is primarily found in specific regions of China, which may make it easier to control the quality and consistency of the source material. In contrast, Glossy Privet Fruit can be found in various Asian countries, which may result in variations in the quality and consistency of the source material.

The content of oleanolic acid in Hemsleya root is about 1.5%~2.0%, while the content in Glossy Privet Fruit is only 0.6%~0.7%. Extraction from Hemsleya roots has a higher yield, which leads to our price advantage.

 

Oleanolic Acid Powder raw material

 

specification sheet

 

Analysis

Specification

Test Method

Assay (Oleanolic Acid)

≥98%

Titration

Specific Rotation

75.0°~ 83.0°

USP

Appearance

white or off-white powder

Visual

Moisture

≤0.5%

USP

Ash

≤0.1%

USP

Particle Size

≥95% Through 80 mesh

USP

Total Heavy Metals

≤10ppm

USP

Cd

≤1.0ppm

ICP-MS

As

≤1.0ppm

ICP-MS

Pb

≤1.0ppm

ICP-MS

Hg

≤1.0ppm

ICP-MS

Total Plate Count

≤1000cfu/g

USP

Fungi and yeast

≤100cfu/g

USP

E. Coli

Negative

USP

Salmonella

Negative

USP

Staphylococcus aureus

Negative

USP

 

super health benefits

Oleanolic Acid Powder has gained recognition for its potential health benefits. This part explores its diverse health benefits, including its protective effects on the liver and ability to modulate macrophages, as well as other potential health benefits.

★ Safeguarding the Liver

Oleanolic acid extract powder exhibits hepatoprotective properties, safeguarding the liver from damage caused by toxins, drugs, and harmful substances. By supporting liver health and reducing oxidative stress, it contributes to optimal detoxification processes and reduces the risk of liver diseases.

a) Detoxification Support: Oleanolic acid extract powder aids in the detoxification process by stimulating enzymes responsible for the breakdown and elimination of toxins. This promotes the efficient removal of harmful compounds from the body, reducing the risk of liver damage and supporting overall detoxification.

b) Anti-fibrotic Effects: Liver fibrosis, characterized by excessive scar tissue formation, can lead to liver cirrhosis and other severe conditions. Oleanolic acid extract powder has shown promising anti-fibrotic effects, inhibiting the deposition of collagen and reducing liver fibrosis. By preventing fibrosis progression, it contributes to the preservation of liver structure and function.

★ Modulating Macrophages

Macrophages are immune cells that play a crucial role in maintaining immune homeostasis and defending against pathogens. Oleanolic acid extract powder demonstrates the ability to modulate macrophage activity, thereby influencing immune responses and promoting overall health.

a) Anti-inflammatory Effects: Macrophages can contribute to inflammation when activated excessively. Oleanolic acid extract powder exhibits anti-inflammatory properties by suppressing the production of inflammatory mediators, thus reducing inflammation. This modulation of macrophage activity helps maintain a balanced immune response and may alleviate inflammation-related diseases.

b) Immune System Regulation: Oleanolic acid extract powder influences macrophage polarization, determining their functional characteristics. It promotes the differentiation of macrophages into an anti-inflammatory phenotype, which aids in tissue repair and immune regulation. This modulation of macrophages contributes to a well-balanced immune system and may support overall immune health.

★ Other Potential Health Benefits

In addition to its hepatoprotective and macrophage-modulating properties, oleanolic acid extract powder offers other potential health benefits.

a) Anti-diabetic Effects: Oleanolic acid extract powder exhibits anti-diabetic effects by improving insulin sensitivity and regulating glucose metabolism. This makes it a promising natural compound for combating diabetes and related complications.

b) Skin Health Benefits: Oleanolic acid extract powder's antioxidant properties make it a potential ingredient in skincare products. It may help protect against skin damage caused by UV radiation and environmental toxins, promoting skin health and reducing signs of aging.

 

Super Health Benefits of Oleanolic Acid Powder

 

production process

The production process of oleanolic acid extract powder extracted from Hemsleya root involves careful sourcing, extraction, purification, and quality control steps. From sourcing high-quality raw materials to obtaining a purified and standardized OA powder, each stage contributes to the production of a premium product. This meticulous process ensures that consumers can benefit from the potential health advantages that oleanolic acid offers.

★ Sourcing and Harvesting Hemsleya Root

Hemsleya root, the plant source of oleanolic acid, is primarily grown in specific regions. The roots are harvested at the appropriate stage of maturity to ensure maximum oleanolic acid content. Careful selection and quality control measures are implemented during this stage to obtain high-quality raw materials.

★ Extraction of Oleanolic Acid

The extraction process plays a crucial role in obtaining oleanolic acid from Hemsleya root. The following steps are typically employed:

a) Grinding and Pulverization: The harvested Hemsleya root is cleaned, dried, and ground into a fine powder. This increases the surface area and facilitates the subsequent extraction process.

b) Solvent Extraction: The powdered Hemsleya root is then subjected to solvent extraction. Commonly used solvents include ethanol or methanol. The powdered root is mixed with the solvent, and the mixture is agitated or sonicated to enhance the extraction efficiency. This process allows the oleanolic acid to dissolve into the solvent.

c) Filtration and Concentration: Once the extraction is complete, the solvent-extract mixture is filtered to remove any solid impurities. The filtrate is then concentrated under reduced pressure to remove the solvent, leaving behind a concentrated oleanolic acid extract.

★ Purification and Isolation

To obtain a purified form of oleanolic acid, further purification and isolation steps are typically carried out:

a) Precipitation or Crystallization: The concentrated extract is subjected to precipitation or crystallization techniques, which involve the addition of suitable solvents or cooling to induce the formation of pure oleanolic acid crystals. This helps separate oleanolic acid from other impurities present in the extract.

b) Filtration and Drying: The obtained oleanolic acid crystals are filtered and washed to remove any remaining impurities. The purified crystals are then dried under controlled conditions to remove residual moisture, resulting in oleanolic acid in powder form.

★ Quality Control and Packaging

To ensure product quality and safety, quality control tests are performed on the oleanolic acid extract powder. These tests may include verifying the oleanolic acid content, assessing purity, and testing for any potential contaminants. Once the product passes quality control standards, it is packaged in suitable containers to protect it from moisture and light, ensuring its stability.

 

Flow Chart

 

our certificates

We are an extraordinary producer and supplier devoting ourselves to producing and supplying our customers around the globe with excellent herbal extracts (powder, oil, liquid, and so on) with high bioavailability. We have multiple international certifications, such as ISO, FDA, Kosher, Halal, FSMA, BRC, and more, to make sure that our final herbal extracts meet stringent requirements and regulations on potency, purity, and quality.

We ensure that the herbal extracts we provide to our global clients are safe, effective, and of high quality, since we completely meet the standards of the aforementioned certifications. Our commitment to the above-mentioned certifications gives our customers peace of mind when they want to work with an outstanding and excellent supplier of superior herbal extracts.

To ensure our herbal extracts comply with these accurate standards, we perform a series of strict and accurate procedures throughout the production process. Each step of the process shows our commitment to the potency, purity, and quality of our herbal extracts, from sourcing raw materials to investing in state-of-the-art production equipment.

 

Our Certificates

 

our packaging

 

Herbal Extract Package

 

our factory

★ A manufacturing plant of about 15,000 square meters

★ FDA, HALAL, Kosher, ISO, and FSMA-certified plants and equipment

★ The total annual production capacity is more than 300 tons

★ Well-equipped for different activities throughout the whole process

★ Rigid process quality control to ensure the stability, safety, and effectiveness of the final product

★ Quality control procedures are documented and maintained

★ Raw materials and final products are stored separately in a large area

 

Our Factory

 

widespread applications

Oleanolic Acid Powder exhibits diverse applications across the pharmaceutical, cosmetics, and food industries, underscoring its versatility and potential impact in various product formulations. As ongoing research continues to unveil its therapeutic properties and safety profile, the utilization of oleanolic acid extract powder is poised to expand, offering innovative solutions for health, wellness, and beauty across multiple sectors.

★ Pharmaceutical Industry

Oleanolic acid extract powder has garnered substantial interest in the pharmaceutical industry due to its pharmacological activities and therapeutic potential. Research has demonstrated its anti-inflammatory and hepatoprotective properties, making it a valuable candidate for drug development.

a. Anti-inflammatory Effects: Oleanolic acid has been studied for its potent anti-inflammatory effects, which make it promising for the treatment of various inflammatory conditions, including arthritis, dermatitis, and inflammatory bowel diseases. Its ability to modulate inflammatory pathways and reduce pro-inflammatory cytokines showcases its potential as an alternative or adjunct therapy in managing inflammatory disorders.

b. Hepatoprotective Activity: The hepatoprotective properties of oleanolic acid make it beneficial in protecting the liver from damage caused by toxins, viruses, and other insults. It has shown promise in mitigating liver injury and supporting liver function, positioning it as a valuable ingredient in formulations targeting liver health and detoxification.

★ Cosmetics Industry

In the cosmetics industry, oleanolic acid extract powder has emerged as a sought-after ingredient for skincare formulations, owing to its skin-friendly properties and multiple benefits for skin health and appearance.

a. Anti-Acne Properties: Oleanolic acid exhibits notable anti-acne properties, making it a valuable inclusion in products targeting acne-prone skin. Its ability to regulate sebum production, inhibit bacterial growth, and reduce inflammation positions it as an effective ingredient in acne treatments, helping to control breakouts and promote clearer skin.

b. Skin Anti-Aging Benefits: The antioxidant and anti-inflammatory properties of oleanolic acid contribute to its anti-aging benefits. By combating oxidative stress, protecting against UV-induced damage, and supporting collagen synthesis, it helps reduce the signs of aging, such as wrinkles, fine lines, and loss of skin elasticity, making it an ideal component in anti-aging skincare formulations.

★ Food Industry

Oleanolic acid extract powder holds potential for application in the food industry, particularly in developing functional food products that offer health-promoting properties beyond basic nutrition.

a. Antioxidant Activity: As a natural triterpenoid with antioxidant activity, oleanolic acid can function as a natural antioxidant in food products, helping to prevent lipid oxidation, extend shelf life, and maintain the quality and nutritional value of foods. Its incorporation into food formulations can contribute to enhancing product stability and preserving freshness.

b. Potential Health Benefits: The bioactive properties of oleanolic acid may offer potential health benefits when incorporated into functional foods. From supporting liver health to exerting anti-inflammatory effects, its inclusion in dietary supplements or health-focused food products holds promise for promoting overall well-being and addressing specific health concerns.

If you are interested in our Oleanolic Acid Extract, please do not hesitate to contact us at bella@inhealthnature.com.

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