Naringenin Powder

Naringenin Powder

OEM & ODM Available
CAS No.: 480-41-1
Botanical Source: Pomelo
Used Part: Peel
Appearance: White Powder
Specification: 98%
Extract Solvent: Ethanol
Test Method: HPLC
Sample: 10-20g
Package: 25kg/drum
Lead Time: 5 days after payment received
Test Report: SGS, Eurofins
Certificate: ISO, Kosher, Halal, FDA, FSMA
MOQ: 10kg

Shaanxi Inhealth Nature Industry Co., Ltd. is one of the most experienced manufacturers and suppliers of naringenin powder in China, featured by quality products and good price. Welcome to wholesale bulk high-grade naringenin powder from our factory. Contact us for free sample.

 

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Your reliable naringenin extract powder supplier

Naringenin Powder belongs to the dihydroflavonoids, is a white crystalline fine powder, with a melting point of 260℃, soluble in ethanol, ether, and benzene, almost insoluble in water, molecular formula C15H12O5, molecular weight 272.25. Naringenin extract is the main flavanone in grapefruit and exists in many fruits and herbs. Naringenin has antibacterial, anti-inflammatory, free radical scavenging, antioxidant, lipid-lowering, liver disease prevention and treatment, platelet aggregation inhibition, anti-atherosclerosis, and other effects. It can be widely used in medicine, food, and other fields.

Inhealth Nature supplies high-quality naringenin extract powder. Our factory and products have passed ISO22000, FSSC22000, Halal, Kosher, and other certifications, and 100,000 cleaning shops can ensure the contamination-free production process. Now, this extract is in stock, and samples are available. We welcome old and new customers to consult our products, and seek technical guidance and business negotiation!

 

Pomelo and Grapefruit Peel Powder

 

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how to improve the bioavailability of naringenin extract?

Improving the bioavailability of naringenin extract-a flavonoid with various health benefits but limited bioavailability due to poor water solubility and low absorption-can be effectively achieved using several advanced drug delivery strategies, such as co-crystallization, liposome, and nanoparticle methods. Each of these methods can enhance the solubility, stability, and absorption of naringenin extract. Here's how each technique works and how it can improve naringenin bioavailability:

 Co-crystallization

a. How it works: Co-crystallization involves the formation of a crystal structure that includes naringenin and another compound (often a co-former) that enhances its properties, such as solubility and stability. The co-former may be a small molecule, salt, or another excipient that interacts with naringenin to improve its dissolution profile.

b. How it improves bioavailability: Co-crystallization can improve naringenin's solubility in aqueous environments by changing its crystal form, which will enhance gastrointestinal absorption. Compared to the pure drug, the co-crystals frequently have superior physicochemical properties, such as a faster dissolution rate.

 Liposome

a. How it works: Liposomes are spherical vesicles made of lipid bilayers that can encapsulate naringenin, allowing it to be transported in a more stable, bioavailable form. Liposomes can be prepared in various sizes, and their surface can be modified to increase cellular uptake.

b. How it improves bioavailability: Liposomes enhance the solubility of naringenin by encapsulating it in a lipid shell, which can improve its stability and protect it from degradation in the digestive tract. By enabling naringenin's entry into cells, including intestinal epithelial cells, through endocytosis, liposomes can enhance its absorption.

 Nanoparticle

a. How it works: Nanoparticles are solid colloidal particles with a size range of 1–1000 nm that can encapsulate naringenin. Biodegradable polymers, lipids, or other substances that allow for targeted delivery and controlled release can be used to create these particles.

b. How it improves bioavailability: Nanoparticles increase the surface area of naringenin, promoting faster dissolution and absorption. Naringenin's bioavailability can be further increased by preventing enzymatic degradation and promoting lymphatic absorption, which avoids the first-pass metabolism.

 

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specification sheet

 

ITEM

SPECIFICATION

TEST METHOD

Active Ingredients

Naringenin

NLT 98%

HPLC

Physical and Chemical Property

Identification

Positive

TLC

Appearance

White Powder

Visual

Odor

Characteristic

Organoleptic

Taste

Characteristic

Organoleptic

Sieve Analysis

100% pass 80 mesh

80 Mesh Screen

Moisture Content

NMT 3.0%

Mettler toledo hb43-s

Residue Analysis

As

NMT 2ppm

Atomic Absorption

Cd

NMT 1ppm

Atomic Absorption

Pb

NMT 3ppm

Atomic Absorption

Hg

NMT 0.1ppm

Atomic Absorption

Heavy Metals

10ppm Max

Atomic Absorption

Microbiological Tests

Total Plate Count

1000cfu/ml Max

AOAC/Petrifilm

Yeast & Mold

100cfu/g Max

AOAC/Petrifilm

Salmonella

Negative in 10 g

AOAC/Neogen Elisa

E.Coli

Negative in 1g

AOAC/Petrifilm

 

Pomelo and Grapefruit Peel Extract

 

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potential health benefits

Here are some potential health benefits of Naringenin Powder:

 Antibacterial Properties

Naringenin extract exhibits antibacterial activity against certain pathogens. It may be used as a natural remedy to fight infections because it can disrupt bacterial cell membranes and stop bacterial growth. Common bacterial strains like Escherichia coli and Staphylococcus aureus may be susceptible to naringenin's effects.

 Anti-inflammatory Effects

Grapefruit peel extract has powerful anti-inflammatory properties, which are attributed to its ability to modulate inflammatory pathways. It can prevent the synthesis of inflammatory mediators like COX-2 (cyclooxygenase-2) and pro-inflammatory cytokines like TNF-α, IL-1β, and IL-6. Because of this, naringenin may be used to manage inflammatory diseases like arthritis, inflammatory bowel disorders, and other chronic inflammatory conditions.

 Antioxidant Activity

Naringenin extract is a potent antioxidant. It can lessen oxidative stress in the body by scavenging free radicals. It shields cells from oxidative stress-induced damage, which is connected to aging, heart disease, and neurodegenerative disorders. Naringenin extract's effect to increase the body's natural antioxidant defense systems, including glutathione peroxidase and superoxide dismutase (SOD), mediates its antioxidant effect.

 Lipid-Lowering Effects

Naringenin extract has a lipid-lowering effect. It may raise high-density lipoprotein (HDL) cholesterol and decrease triglycerides, total cholesterol, and low-density lipoprotein (LDL) cholesterol-all of which are good for heart health. Naringenin functions by enhancing the liver's lipid metabolism and preventing the activity of enzymes that are necessary for the synthesis of cholesterol.

 Prevention and Treatment of Liver Disease

Naringenin extract shows promise in shielding the liver from many damage, such as fatty liver disease and alcohol-induced liver injury. It works by reducing inflammation, oxidative stress, and liver fibrosis. A crucial regulator of antioxidant defense that contributes to liver protection, nuclear factor erythroid 2–related factor 2 (Nrf2), can be activated by naringenin. It has also been shown to regulate lipid metabolism and reduce hepatic fat accumulation, which is a significant risk factor for conditions like non-alcoholic fatty liver disease (NAFLD).

 

Health Benefits of Naringenin Powder

 

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our certificates

As an experienced and skilled manufacturer and supplier, we pledge to produce and offer our global customers superior herbal extracts (powder, oil, liquid, etc.) that are safe and have a high bioavailability. Due to our several international certifications, including ISO, FSSC, FDA, Kosher, Halal, FSMA, and others, we can ensure that the final herbal extracts we sell adhere to strict standards and regulations regarding potency, quality, and purity.

Because of our complete compliance with the aforementioned international certifications, our clients worldwide can be certain of the safety, effectiveness, and high bioavailability of the herbal extracts we offer. When clients seek to collaborate with an outstanding and dependable provider of premium herbal extracts, our commitment to the aforementioned certifications offers them peace of mind.

Throughout the whole production process, we employ several exacting and rigorous procedures to ensure that our herbal extracts live up to these high standards. At every step of the process, from purchasing raw materials to investing in state-of-the-art production equipment, our dedication to ensuring the potency, purity, and quality of our herbal extracts is apparent.

 

Our Certificates

 

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our factory

With cutting-edge production equipment, comprehensive inspection devices, advanced purification systems, and a qualified workforce, we ensure the production of high-quality herbal extracts. By prioritizing excellence in every aspect of the production process, we strive to meet customer expectations, maintain product reliability, and contribute to the advancement of the global phytochemical industry.

 

Inhealthnature Factory

 

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our packaging

 

Herbal Extract Package

 

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naringenin extract applications

Below are some of the primary applications of Naringenin Powder in food, health care products, and pharmaceuticals:

★ Food Industry

a. Antioxidant Additive: Due to its antioxidant properties, naringenin extract helps protect food from oxidative damage, thus extending shelf life. It can be used in food preservation.

b. Functional Foods and Beverages: This extract can be incorporated into health-oriented foods and drinks, including juices, smoothies, and fortified foods. It is considered beneficial for gut health and may support immune function, making it popular in health drinks and supplements.

c. Weight Management: Naringenin extract is sometimes added to weight management or fat-burning products because of its potential to enhance metabolism and reduce fat accumulation.

★ Health Care Products

a. Antioxidant Supplements: Naringenin extract is known for its strong antioxidant properties, which can help reduce oxidative stress in the body, contributing to overall health and preventing chronic diseases such as heart disease and diabetes. It's often included in dietary supplements aimed at promoting general well-being.

b. Skin Care: It has been explored in skincare products for its potential to reduce oxidative damage, improve skin tone, and protect against UV-induced skin damage. It may be found in lotions, serums, and creams aimed at anti-aging.

c. Cholesterol-Lowering Products: Naringenin extract has shown the potential to lower blood cholesterol levels, making it a common ingredient in health products aimed at supporting cardiovascular health and regulating lipid levels.

★ Pharmaceuticals

a. Neuroprotective Properties: Some research suggests that naringenin extract may offer neuroprotective benefits, potentially aiding in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's disease by reducing oxidative stress and inflammation in the brain.

b. Antiviral and Antibacterial: This extract has antiviral and antibacterial properties, it can be used in the development of treatments for various infections. It has been investigated for its role in combatting viruses like the flu and certain bacteria.

c. Liver Health: Naringenin extract has hepatoprotective effects, meaning it can help protect the liver from damage caused by toxins, excessive alcohol consumption, or certain medications. It's sometimes included in formulations for liver health supplements.

 

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our OEM Service

We support customers to personalize labels and bottles, 250g, 500g bags, aluminum foil bags, or jars. We can also customize products depending on the customer's needs. Additionally, we can personalize labels and place aluminum foil bags for clients.

 

Our OEM Service Flow Chart

 

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you can find us here

Shaanxi Inhealth Nature Industry Co., Ltd

Tel: 86-29-88387688

Mobile: +86-18991583980

WhatsApp: +86-18991583980

Email: shaw@inhealthnature.com

Send your inquiry to us and we will reply to you within 24 hours.

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