Shikimic Acid Powder

Shaanxi Inhealth Nature Industry Co., Ltd. is one of the most experienced manufacturers and suppliers of shikimic acid powder in China, featured by quality products and good price. Welcome to wholesale bulk high-grade shikimic acid powder from our factory. Contact us for free sample.

Shikimic Acid Powder is derived from star anise. It is a white crystalline powder. The most common specification of this powder is 98%, detected via HPLC (High-Performance Liquid Chromatography). Higher purities like 99%, 99.5%, and 99.9% are also available for more specialised applications. Shikimic acid extract is the key raw material for Oseltamivir. The main health benefits of this extract are its antiviral, anti-inflammatory, and analgesic effects. It is often used in dietary supplements to support immune system function. Besides, it can soothe irritated skin and help with conditions like acne, eczema, and psoriasis.

Our shikimic acid extract is refined using advanced bio-enzymatic hydrolysis and purification technology, maintaining a purity consistently above 98%. It exhibits excellent water solubility and maintains good solubility and stability in various formulations. Our ISO 22000 and other quality management system certifications ensure full traceability from raw materials to finished products and meet the regulatory requirements of different global markets (such as Europe and North America). We can tailor and optimise the formulation and specifications of our shikimic acid extract based on specific application scenarios, such as pharmaceutical intermediates and raw materials for health supplements, to meet the unique requirements of different markets. We have an annual production capacity of 4,000 tons and process 600 kg of raw materials daily. This robust production capability ensures a reliable supply chain and guarantees stable, timely product delivery for our customers.

We employ a combined enzymatic hydrolysis and yeast fermentation extraction method to obtain shikimic acid. Only water-based solvents are used throughout the process; no organic reagents are employed. The resulting shikimic acid is of high purity, with a content greater than 99%, and the powder is pure white, without bitterness, solvent residue, or pesticide residue. The specific extraction process is as follows:

1. Pretreatment and Enzymatic Hydrolysis: Star anise is pulverised with water and then hydrolysed for 1-3 hours at 45-60℃ with 0.1%-0.5% by weight of a biological enzyme (such as pectinase or cellulase).

2. Organic Membrane Filtration: The hydrolysate is filtered in two stages using organic membranes with molecular weight cutoffs of 8000 and 800, respectively, and pressures of 0.45-0.5 MPa and 1.8-2.0 MPa.

3. Yeast Fermentation: The filtrate is aerobically fermented at 30-35℃ at a star anise to yeast mass ratio of 1:0.001 to 1:0.015 for 36-48 hours.

4. Concentration: The fermented filtrate is concentrated to a solids content greater than 50% (Brix), and the pH of the concentrate is adjusted to 1.0-1.5.

5. Crystallisation: The concentrate is crystallised at a low temperature of 4-10℃ for more than 4 hours to precipitate shikimic acid.

6. Drying: Finally, the crystallised material is dried using spray drying to obtain the shikimic acid extract.

Shikimic Acid Powder is a versatile ingredient with significant applications across several industries.

 Pharmaceutical Applications

Antiviral Agent: The pharmaceutical industry relies heavily on shikimic acid as a critical starting material for the industrial synthesis of the antiviral drug Oseltamivir. This application is crucial for treating and preventing various strains of the influenza virus.

 Cosmetic and Skincare Uses

In cosmetics, shikimic acid is valued for many skin benefits. A clinical study on formulations containing 3% shikimic acid found it effective in improving skin microrelief and promoting exfoliation. Its official functions as a cosmetic ingredient include:

a. Anti-Seborrheic: Helps control excess sebum production, benefiting those with oily skin or seborrheic dermatitis.

b. Skin Conditioning: Helps maintain skin softness, smoothness, and hydration.

c. Exfoliation: Promotes desquamation (shedding of the outer skin layers), leading to a more flexible and compact skin surface.

 Dietary Supplement and Functional Food Role

Shikimic acid is a nutraceutical ingredient in forms like capsules and tablets. The reported benefits include:

a. Antioxidant Effect: It helps neutralise free radicals, protecting cells from oxidative damage.

b. Anti-inflammatory Properties: It can help alleviate inflammatory reactions and related symptoms.

c. Immune Function Support: It may enhance the activity of immune cells, such as natural killer cells and regulatory T-cells, which improves the body's defence against infections.

 Agricultural Applications

In agriculture, shikimic acid finds application as a biological regulator. It can:

a. Promote Plant Growth: Enhance the development and yield of crops.

b. Enhance Disease Resistance: Strengthen plants' natural defences against diseases.

With cutting-edge production equipment, comprehensive inspection devices, advanced purification systems, and a qualified workforce, we ensure the production of high-quality herbal extracts. By prioritizing excellence in every aspect of the production process, we strive to meet customer expectations, maintain product reliability, and contribute to the advancement of the global phytochemical industry.

As an experienced and skilled manufacturer and supplier, we pledge to produce and offer our global customers superior herbal extracts (powder, oil, liquid, etc.) that are safe and have a high bioavailability. Due to our several international certifications, including ISO, FSSC, FDA, Kosher, Halal, FSMA, and others, we can ensure that the final herbal extracts we sell adhere to strict standards and regulations regarding potency, quality, and purity.

Because of our complete compliance with the aforementioned international certifications, our clients worldwide can be certain of the safety, effectiveness, and high bioavailability of the herbal extracts we offer. When clients seek to collaborate with an outstanding and dependable provider of premium herbal extracts, our commitment to the aforementioned certifications offers them peace of mind.

★ Packaging Form

a. The bulk goods are 25 Kg/Drum, the inner is a double plastic bag.

b. The minimum package form is 1 Kg/aluminium foil bag.

c. The products should be stored in a dry and cool place, keeping away from strong light and heat.

d. The expiration date is 2 years (24 months) when properly stored.

★ Shipping Method

a. Below 50 Kg, we suggest you ship the goods by FEDEX, DHL, UPS, TNT, etc.

b. More than 50 Kg, we suggest you ship the goods by air.

c. Above 500 Kg, we suggest you ship the goods by sea.

★ Before-Sale Service

1) Provide a 10-20g free sample for your test.

2) Robust technical support from our R&D team and factory.

3) Gives comprehensive solutions to your product.

4) Has a full set of technical data, such as COA, MOA, MSDS, Flow Chart, Test Reports, etc.

★ After-Sale Service

1) Provides real-time shipping information.

2) Assists in customs clearance.

3) Perfect product traceability system and service.

4) Complete product quality assurance.

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