Alpha GPC 50% Powder
Natural Nootropic Ingredient
Excellent quality, Reasonable price, Professional service
Cooperation with an authoritative third-party testing institution
Stable Inventory: 300kg
CAS Number: 28319-77-9
Specification: 50%
Appearance: White to off-white powder
Package: 25kg/drum
Lead time: 5 days after payment is received
Features: Vegan, Gluten-Free, Non-GMO, Non-ETO
Certificate: ISO, Kosher, Halal, FDA, FSMA
Delivery: FedEx, DHL, Ship by air, Ship by sea
MOQ: 5kg
Free Sample: 10-20g
Shaanxi Inhealth Nature Industry Co., Ltd. is one of the most experienced manufacturers and suppliers of alpha gpc 50% powder in China, featured by quality products and good price. Welcome to wholesale bulk high-grade alpha gpc 50% powder from our factory. Contact us for free sample.
ISO-Certified Alpha GPC Powder Manufacturer
Alpha GPC 50% Powder is a premium, highly bioavailable choline compound widely recognized as one of the most effective nootropic supplements for boosting cognitive function, memory, focus, and physical performance. It efficiently crosses the blood-brain barrier to increase acetylcholine levels, support mental clarity, and improve neuromuscular function.
Alpha GPC powder is a free-flowing, white to off-white powder formulated with 50% active L-Alpha-glycerylphosphorylcholine and 50% anti-caking agents such as silicon dioxide or dicalcium phosphate. Since pure Alpha GPC is extremely hygroscopic and tends to absorb moisture from the air, these excipients are essential for improving product stability. The result is a stable, easy-to-handle powder ideal for dietary supplement formulations.
Our Alpha GPC powder is produced through a rigorously controlled production process that ensures exceptional purity, consistency, and regulatory compliance. Our production process guarantees:
a. High purity and stability through precise formulation with anti-caking agents
b. Batch-to-batch consistency ensures reliable performance
c. Compliance with international regulatory requirements for dietary supplements
d. State-of-the-art facilities and experienced technical teams dedicated to quality assurance
Alpha GPC's health benefits are recognized by regulatory authorities and markets worldwide. Beyond its use as a prescription pharmaceutical in several countries, it is widely consumed as a dietary supplement. Alpha GPC has been approved as a Novel Food ingredient by Health Canada in 2023 and by China's National Health Commission in 2024, respectively. These regulatory approvals confirm its excellent safety profile and health benefits. This is why Alpha GPC is now a trusted ingredient, with expanding applications in the food and supplement industries.
Your Selected and Reliable Partner in Natural Ingredients
Tell us your ingredient needs, we'll customize the perfect botanical solutions and formulations to enhance your brand value and bring about multiple business potentials.
Why partner with Inhealth Nature for alpha GPC powder?
Trusted and Reliable Expertise
Inhealth Nature is a premium herbal extract manufacturer with excellent quality control and product traceability. Our skilled team is exceptional at formulation and production, guaranteeing that each batch satisfies the highest requirements for efficacy and quality.
Tailored Formulations
We work closely with you to develop the exact product that you desire to cater to your customers and enhance your brand's competitive edge. We customize ingredients, formulations, and solutions to perfectly match your product potential.
Top Ingredient Sourcing
We select only the top-notch raw materials to maximize your product's potency and performance. Trust in our rigorous sourcing standards to give you a competitive edge.
Strict Quality Control
Quality is the cornerstone of Inhealth Nature's manufacturing approach. We perform the highest standards through rigorous testing and comprehensive quality control, ensuring every herbal extract is safe, effective, and fully compliant with industry regulations. With Inhealth Nature, you can trust that your brand's reputation is safeguarded batch after batch.
specification sheet
|
Items |
Specifications |
Analysis Method |
|
Appearance |
White to off-white powder, hygroscopic |
Visual |
|
Identification |
Conforms to the standard |
TLC |
|
Specific optical rotation |
D25 -2.7° (c = 2.7 in water, pH 2.5); D25 -2.8° (c = 2.6 in water, pH 5.8) |
USP |
|
Moisture |
<3.0% |
KF |
|
Heavy metals |
<10ppm |
Colorimetry |
|
Total plate count |
≤1000cfu/g |
USP |
|
Yeast and mold |
≤100cfu/g |
USP |
|
Coliforms |
Negative |
USP |
|
Salmonella |
Negative |
USP |
|
Assay (dried basis) |
≥50% |
Potentiometric Titration |
|
Composition |
Dihydrate Calcium Phosphate: 43.5~48.5%; Silicon Dioxide: 0.5~1.5% |
|
production process
At Inhealth Nature, our Alpha GPC Powder is manufactured through a rigorously controlled production process, from raw material reaction to final drying. This ensures that every batch meets the highest standards of purity, consistency, and compliance with market demands and strict regulatory requirements.
1. Reaction Phase: The two main reactants, (R)-(-)-3-Chloro-1,2-propanediol and PC-Na, are mixed in 85% ethanol solution. This mixture is then heated under reflux for 20 hours to facilitate the substitution reaction, yielding crude GPC.
2. Cooling: After the reaction is complete, the solution is cooled down to 5°C, which promotes the precipitation of by-products and unreacted salts from the mixture.
3. Centrifugal Separation: The cooled mixture is transferred to a centrifuge, where the solid precipitates are separated from the liquid phase that contains the crude GPC product.
4. Resin Adsorption Column: The liquid containing crude GPC passes through a resin adsorption column, which selectively retains either the GPC molecules or specific impurities, depending on the resin configuration.
5. Elution: The resin column is eluted with 85% ethanol to recover the GPC-rich fraction, separating it from impurities that remain bound to the resin.
6. Solvent Replacement: The solvent system is switched from ethanol to water by gradually removing ethanol under controlled conditions and adding water, preparing the solution for subsequent ion-exchange purification.
7. Mixed Bed Column: The aqueous solution passes through a mixed bed ion-exchange column containing both cation and anion exchange resins, which remove residual ionic impurities such as unreacted salts and catalyst traces.
8. Testing: The purified intermediate solution undergoes quality control testing to verify that it meets the required specifications before proceeding to final processing steps.
9. Vacuum Distillation: The solution is concentrated under reduced pressure through vacuum distillation, which removes excess water and solvent while minimizing thermal degradation of the product.
10. Activated Carbon Treatment: The concentrated solution is stirred with activated carbon for one hour, which adsorbs colored impurities and organic contaminants to improve product purity and appearance.
11. Filter Press: The mixture is passed through a filter press to completely remove the spent activated carbon, yielding a clear purified solution.
12. Final Vacuum Distillation: The clarified solution undergoes a second vacuum distillation to further concentrate the GPC to its final, pure form with the appropriate solids content.
13. Silicon Dioxide Addition: Silicon dioxide is added to the concentrated GPC solution as a carrier and stabilizer, formulated to achieve a final product specification of 50% GPC content.
14. Drying: The mixture is dried using appropriate methods to remove residual moisture, transforming the liquid formulation into a free-flowing powder.
15. Finished Product: The resulting material is Alpha GPC Powder (50%), a standardized product ready for packaging and distribution.
main health benefits
Here are the main health benefits of Alpha GPC 50% Powder:
a. Cognitive Enhancement: It improves memory, focus, and mental clarity by increasing acetylcholine levels, a neurotransmitter essential for brain function.
b. Physical Performance: It increases explosive strength, power output, and endurance, making it a popular pre-workout supplement for athletes.
c. Neuroprotection and Brain Health: Research suggests it helps maintain cognitive function in older adults and may support recovery from stroke or cognitive decline.
d. Growth Hormone Stimulation: Supplementation has been shown to increase growth hormone secretion, aiding in muscle development and recovery.
e. Improved Motivation: Some studies indicate that it can increase motivation and mental energy.
product applications
Here is an overview of the product applications of Alpha GPC 50% Powder:
Nootropic Supplements
A. In the nootropic market, Alpha GPC powder is a common ingredient for formulations targeting memory enhancement, focus, and overall cognitive function. It is highly valued for its ability to cross the blood-brain barrier and increase acetylcholine synthesis.
B. Common Dosage: A typical serving provides 300 mg to 600 mg of Alpha-GPC. Clinical studies often use 1200 mg daily for cognitive support.
C. Common Formulations: It is widely available in capsules, tablets, and powder form. It is often featured in stacked nootropic products designed for daily cognitive support.
D. Synergistic Ingredients: To maximize cognitive benefits, Alpha GPC is frequently combined with:
- Huperzine A: An acetylcholine esterase inhibitor that helps maintain higher levels of acetylcholine in the brain.
- Bacopa Monnieri: An herb known for its memory-enhancing properties.
- Phosphatidylserine: Another phospholipid that supports brain cell membrane integrity and function.
Sports Nutrition
A. Alpha GPC is a popular ingredient in sports nutrition, particularly in pre-workout supplements, due to its potential to enhance power output, strength, and focus during training.
B. Common Dosage: A typical pre-workout serving provides between 300 mg and 750 mg of Alpha GPC.
C. Common Formulations: It is primarily found in pre-workout powders and capsules.
D. Synergistic Ingredients: In sports supplements, Alpha GPC is combined with ingredients that support energy, focus, and performance, such as:
- Beta-Alanine: To buffer muscle acid and improve endurance.
- Creatine Monohydrate: To support strength and power output.
- L-Citrulline or L-Arginine: To promote nitric oxide production for better blood flow and muscle pumps.
Dietary Supplements
A. Alpha GPC Powder is a preferred raw material for supplement manufacturers due to its stability and ease of handling. The 50% formulation, often combined with carriers like silicon dioxide or dicalcium phosphate, ensures a consistent, free-flowing powder ideal for encapsulation.
B. Common Formulations: This includes capsules or tablets where the dosage is precisely controlled.
C. Manufacturing Advantage: The powder blends uniformly with other ingredients, making it suitable for high-speed encapsulation and tablet pressing processes.
Functional Foods
A. Beyond traditional supplements, Alpha GPC is increasingly incorporated into functional foods and beverages aimed at cognitive health and healthy aging. It is particularly relevant for products targeting the silver generation (older adults).
B. Common Applications: It can be found in functional beverages, nutritional shakes, and brain-health bars.
C. Formulation Considerations: When used in foods and beverages, the focus is on masking any potential bitterness and ensuring the stability of the Alpha GPC throughout the product's shelf life.
our cerificates
As an experienced and skilled manufacturer and supplier, we pledge to produce and offer our global customers superior herbal extracts (powder, oil, liquid, etc.) that are safe and have a high bioavailability. Due to our several international certifications, including ISO, FSSC, FDA, Kosher, Halal, FSMA, and others, we can ensure that the final herbal extracts we sell adhere to strict standards and regulations regarding potency, quality, and purity.
Because of our complete compliance with the aforementioned international certifications, our clients worldwide can be certain of the safety, effectiveness, and high bioavailability of the herbal extracts we offer. When clients seek to collaborate with an outstanding and dependable provider of premium herbal extracts, our commitment to the aforementioned certifications offers them peace of mind.
our factory
a. We are a leading herbal extract manufacturer with more than 11 years of industry experience.
b. We have over 300 products for you to choose from, including monomers, standardized extracts, plant powders, essential oils, supercritical CO2 extracts, fermented nutrients, and food additives.
c. We have a clean workshop and cutting-edge equipment as per GMP standards.
d. We have sophisticated and experienced R&D and service teams to support you.
our OEM Services
Inhealth Nature is dedicated to providing premium Alpha GPC ingredients to the global nootropic supplements, sports nutrition, dietary supplements, and functional foods industries. We offer versatile delivery formats, including capsules, tablets, and powder, and also integrate Alpha GPC into functional foods and beverages. Inhealth Nature goes beyond standard supply by offering custom formulation services.
FAQ
Q1: Is Alpha GPC Powder safe?
A: Alpha GPC powder is generally well-tolerated when used appropriately. It has been used orally at doses of 1200 mg daily for up to 6 months with apparent safety. Intramuscular administration at doses of 1000-1200 mg daily for 28 to 90 days has also shown apparent safety.
However, some individuals may experience mild adverse effects. Orally, Alpha GPC has been rarely associated with gastrointestinal issues (diarrhea, heartburn, nausea, and vomiting), neurological symptoms (dizziness, excitation, headache, and insomnia), and skin rash.
Q2: Why is Alpha GPC powder (50%) formulated with carriers instead of sold as 100% pure?
A: Pure Alpha GPC is extremely hygroscopic, meaning it rapidly absorbs moisture from the air, leading to clumping, degradation, and reduced shelf life. Formulating it as a 50% powder with carriers such as starch, silicon dioxide, or dicalcium phosphate significantly improves stability, handling, and flowability. This ensures a consistent, high-quality product that is practical for manufacturing and safe for consumers.
Q3: How can I verify the quality of Alpha GPC Powder?
A: Quality is verified through a Certificate of Analysis (COA) that includes key specifications such as appearance, identification, specific optical rotation, moisture content (<3.0%), heavy metals (<10ppm), microbial limits, and assay (≥50% by potentiometric titration). Reputable suppliers also provide third-party lab testing and comply with regulatory standards.
Q4: Can I use Alpha GPC Powder if I am vegetarian or vegan?
A: Yes, Alpha GPC Powder is typically suitable for vegetarians and vegans. The active ingredient is synthetic or derived from non-animal sources, and common carriers like starch, silicon dioxide, and dicalcium phosphate are plant-based or mineral-based. However, always check the specific product label or confirm with the manufacturer to ensure no animal-derived excipients are used.
Q5: How should I store Alpha GPC powder to keep it fresh?
A: Even though the 50% concentration makes it less hygroscopic than pure Alpha GPC, proper storage is still key to maintaining its quality and preventing clumping.
Storage Best Methods: Keep the powder in a cool, dry place, away from direct sunlight, heat, and moisture. Always ensure the container is tightly sealed immediately after each use. Avoid storing it in the bathroom or near the kitchen sink.
Q6: What is the difference between Alpha GPC, Citicoline, and Choline Bitartrate?
A: These are all sources of choline, but they differ in how the body processes them and their effects.
a. Alpha GPC: Considered one of the most effective choline sources because it delivers choline directly to the brain by efficiently crossing the blood-brain barrier. It is often preferred for its cognitive and physical performance benefits.
b. Citicoline (CDP-Choline): Another high-quality choline source that breaks down into choline and uridine in the body. It is also excellent for brain health and is often compared favorably to Alpha GPC. The choice between them is often a matter of personal preference.
c. Choline Bitartrate: A basic and inexpensive choline salt. It is poorly absorbed by the brain and is primarily used by the body for other functions. It is less effective for targeted cognitive enhancement compared to Alpha GPC or Citicoline.
Q7: How do I calculate my dosage with 50% powder?
A: This is the most common point of confusion. Because the powder is only 50% Alpha GPC, you need to take twice the amount of powder to get your desired dose of the active ingredient.
1) The Math: If you want a 600 mg dose of pure Alpha GPC, you need to measure out 1200 mg of the 50% powder (since 1200 mg x 50% = 600 mg).
2) General Rule: A typical daily dose of Alpha GPC ranges from 300 mg to 1200 mg of the active ingredient. Therefore, you would need to take between 600 mg and 2400 mg of the 50% powder to achieve that range.
our before-sale and after-sale services
★ Before-Sale Service
1) Provide a 10-20g free sample for your test.
2) Robust technical support from our R&D team and factory.
3) Gives comprehensive solutions to your product.
4) Has a full set of technical data, such as COA, MOA, MSDS, Flow Chart, Test Reports, etc.
★ After-Sale Service
1) Provides real-time shipping information.
2) Assists in customs clearance.
3) Perfect product traceability system and service.
4) Complete product quality assurance.
You can Find us here
Inhealth Nature has been focused on the R&D and production of Alpha GPC powder for more than 12 years since 2014. Are you looking for reliable partner for your formulations? Welcome to contact us.
Our address
802, B2, Jingye Building, Jinye Road, Xi'an, 710065, China
Phone Number
+86-18709243507
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