Pineapple Enzyme Bromelain

Pineapple Enzyme Bromelain

Your Reliable Bromelain Enzyme Powder Manufacturer
Our OEM Dosage Forms: Capsules, Tablets, Topical Creams, and Powders
CAS No.: 9001-00-7
Grade: Food & Pharmaceutical Grade
Botanical Source: Pineapple Stem
Specification: 50000u/g-1500000u/g
Appearance: White to Light Yellow Powder
Package: 20kg/drum or 25kg/drum
Lead time: 7 days after payment received
Storage: Store in the original tightly closed package from moisture and sunlight
Test Report: SGS, Eurofins
Certificate: ISO, Kosher, Halal, FDA, FSMA
Free Sample: 10-20g
Delivery: FedEx, DHL, Ship by air, Ship by sea
MOQ: 10kg

Shaanxi Inhealth Nature Industry Co., Ltd. is one of the most experienced manufacturers and suppliers of pineapple enzyme bromelain in China, featured by quality products and good price. Welcome to wholesale bulk high-grade pineapple enzyme bromelain from our factory. Contact us for free sample.

 

your reliable bromelain enzyme powder manufacturer

Our Pineapple Enzyme Bromelain is a highly concentrated proteolytic complex extracted from the stems of the pineapple plant (Ananas comosus). It is specifically sourced from pineapple stems as they contain a significantly higher concentration of bromelain compared to the fruit flesh, ensuring superior potency and efficacy. Bromelain is not a single enzyme, but a rich mixture of several thiol-endopeptidases and other beneficial components. The active ingredients include: phosphatases, glycosidases, peroxidases, cellulases, escharases, and several protease inhibitors. Bromelain is recognized by the U.S. Food and Drug Administration (FDA) as Generally Recognized As Safe (GRAS). It is well-tolerated by most individuals when used as directed.

This unique blend of enzymes contributes to a wide range of documented health benefits:

a. Anti-inflammatory: Helps reduce swelling and inflammation.

b. Digestive Aid: Promotes the breakdown and absorption of proteins in the digestive tract.

c. Analgesic (Pain Relief): Helps alleviate pain and discomfort.

d. Sinusitis & Osteoarthritis Relief: Helps reduce symptoms associated with sinus inflammation and joint pain.

e. Burn Debridement: Used in topical formulations to selectively remove dead tissue from burns.

f. Enhanced Drug Absorption: Studies indicate it can improve the absorption of certain medications, especially antibiotics.

Bromelain enzyme powder's versatility makes it a valuable ingredient across multiple industries:

1. Health Products: Dietary supplements, capsules, and tablets.

2. Cosmetics: Skincare formulations for their exfoliating and soothing properties.

3. Foods: Used as a natural processing aid.

4. Meat Tenderizer: Effectively breaks down protein, making meat more tender.

5. Animal Feed: An additive to promote animal health.

Our enzyme activity preservation technology enables brommelain powder to have high heat resistance and stability. Under conditions of 80 degrees centigrade, the preservation rate of enzyme activity after 5 days is more than 96%, whereas the bromelain powder of other suppliers on the market is approximately 45%. Our high-quality products can also reach pharmaceutical grade. The advantages of Inhealth Nature as a leading manufacturer of high-quality Bromelain Enzyme Powder are as follows:

 Standardized potency for consistent, reliable results.

 Strict quality control from raw material sourcing to the final product.

 Manufacturing processes that preserve the full spectrum of enzymatic activity.

 A commitment to purity, safety, and customer satisfaction.

 

Bromelain Enzyme Powder

 

product specification

 

ITEMS OF ANALYSIS

SPECIFICATIONS

RESULTS

Appearance

White to light yellow powder

Conform

Odor

The characteristic smell of Pineapple

Conform

Mesh

98% pass 100 mesh

Conform

PH

5.0-8.0 pH (1% aqua)

Conform

Activity of the enzyme

50000U/g

52000U/g

Loss on drying

≤5.0%

2.70%

Loss on ignition

≤5.0%

2.82%

Heavy metals (as Pb)

≤20mg/kg

<20mg/kg

As

≤2.0mg/kg

<2.0mg/kg

Microbiology

Total Plate Count

<1000cfu/g

820cfu/g

Yeast and Mould

<100cfu/g

<100cfu/g

E.Coli

Absent/g

Absent

Staphylococcus aureus

Absent/g

Absent

Salmonella

None detected in 10g

Absent

Storage

STORED AWAY FROM MOISTURE
(RH LESS THAN 60) AT A TEMPERATURE BELOW 25℃

Shelf Life

12 months

 

Pineapple and Bromelain Enzyme Powder

 

bromelain production process

We have sufficient Pineapple raw material, obtain natural and sustainable Bromelain, minimize cost, and after strict internal and external lab tests, you can get our high-quality products. The production process of our bromelain powder is as follows:

1. Adsorption: Pass the juice extracted from the pineapple stem through the adsorption column for adsorption, controlling the flow rate at 800-1000 L/h.

2. Elution: Stop loading the column when the collected volume reaches 5 billion enzyme activity units. After stopping loading, neutralize the adsorbent with 15% NaOH until the effluent pH reaches 7.0. Drain the remaining liquid, then soak in a 7-9% NaCl solution for 30 minutes for elution. Control the elution flow rate and collect the eluate.

3. Acidification and Salting-Out: Add hydrochloric acid to the eluate to adjust the pH to 5.0. Then, add sulfate (usually ammonium sulfate) at 25% by weight of the filtrate. Once completely dissolved, allow to stand at 4°C for 12 hours.

4. Centrifugation and Washing: Centrifuge the mixture after salting-out, and rinse the precipitate 2-3 times with 4°C purified water to obtain crude bromelain.

5. Dissolution and purification: Place the crude enzyme in a dissolution tank and add 10 times the amount of purified water. While stirring, adjust the pH to 7.0-7.5 with 20% NaOH to completely dissolve the enzyme. Once the solution becomes clear, filter to obtain the filtrate.

6. Refining and precipitation: While stirring, slowly adjust the pH of the filtrate to 4.0 with hydrochloric acid. Let it stand for 1 hour to allow the enzyme to precipitate again.

7. Centrifugation: Centrifuge the precipitated enzyme mixture from the refining tank for 20-30 minutes. Rinse the precipitate 2-3 times with cold purified water to obtain the wet bromelain product.

8. Sieving and vacuum drying: Pass the wet product through a 20-mesh sieve, then vacuum dry it at room temperature for 4-8 hours under a vacuum of -0.08-0.09 MPa, controlling the moisture content to below 0.2%, to obtain the dry product.

9. Screening and packaging: The dry product is screened through a 100-mesh sieve, packaged at 20kg/barrel or 25kg/barrel, tested, and put into storage.

 

Inhealth Nature Pineapple Enzyme Bromelain Production Flow Chart

 

bromelain health benefits

Next, let's take a look at the health benefits of Pineapple Enzyme Bromelain.

 Anti-inflammatory Properties

Bromelain enzyme powder exhibits significant anti-inflammatory effects by modulating the immune system and reducing pro-inflammatory compounds such as prostaglandins and bradykinin. It may decrease the secretion of cytokines like IL-1β, IL-6, and TNF-α in conditions of inflammation, making it beneficial for managing various inflammatory disorders.

 Digestive Aid

As a proteolytic enzyme, bromelain assists in the breakdown of proteins into peptides and amino acids, thereby enhancing protein digestion and nutrient absorption. This can be particularly helpful for individuals experiencing bloating or discomfort after meals, and it may alleviate symptoms associated with digestive issues like indigestion or irritable bowel syndrome.

 Analgesic (Pain Relief)

Bromelain powder possesses analgesic properties that help reduce pain, particularly in conditions such as osteoarthritis, sports injuries, and post-surgical trauma. Its pain-relieving effects are thought to stem from its ability to diminish inflammatory mediators like bradykinin, which is involved in pain perception.

 Sinusitis & Osteoarthritis Relief

Clinical studies indicate that bromelain can alleviate symptoms of sinusitis by reducing mucus viscosity, swelling, and congestion in the nasal passages. In osteoarthritis, bromelain supplementation has been found to significantly reduce pain and stiffness, with some research showing efficacy comparable to conventional anti-inflammatory drugs like diclofenac.

 Burn Debridement

Bromelain is used in topical applications to selectively remove dead or damaged tissue from burns and wounds without harming adjacent healthy skin, a process known as debridement. This enzymatic action can accelerate healing and prepare the wound bed for skin grafting.

 Enhanced Drug Absorption

Bromelain can improve the absorption and efficacy of certain medications, particularly antibiotics such as amoxicillin and tetracycline. By promoting better distribution of these drugs at the site of infection, bromelain may help reduce the required dosage and minimize side effects.

 

Pineapple Enzyme Bromelain Health Benefits

 

our before-sale and after-sale services

★ Before-Sale Service

1) Provide a 10-20g free sample for your test.

2) Robust technical support from our R&D team and factory.

3) Gives comprehensive solutions to your product.

4) Has a full set of technical data, such as COA, MOA, MSDS, Flow Chart, Test Reports, etc.

★ After-Sale Service

1) Provides real-time shipping information.

2) Assists in customs clearance.

3) Perfect product traceability system and service.

4) Complete product quality assurance.

 

our factory

a. We are a leading herbal extract manufacturer with more than 11 years of industry experience.

b. We have over 300 products for you to choose from, including monomers, standardized extracts, plant powders, essential oils, supercritical CO2 extracts, fermented nutrients, and food additives.

c. We have a clean workshop and cutting-edge equipment as per GMP standards.

d. We have sophisticated and experienced R&D and service teams to support you.

Steam Distrillation Equipment

Supercritical Co2 Extraction Equipment

Inspection Device-1

Inspection Device

 

our certificates

As an experienced and skilled manufacturer and supplier, we pledge to produce and offer our global customers superior herbal extracts (powder, oil, liquid, etc.) that are safe and have a high bioavailability. Due to our several international certifications, including ISO, FSSC, FDA, Kosher, Halal, FSMA, and others, we can ensure that the final herbal extracts we sell adhere to strict standards and regulations regarding potency, quality, and purity.

Because of our complete compliance with the aforementioned international certifications, our clients worldwide can be certain of the safety, effectiveness, and high bioavailability of the herbal extracts we offer. When clients seek to collaborate with an outstanding and dependable provider of premium herbal extracts, our commitment to the aforementioned certifications offers them peace of mind.

 

Our Certificates

 

our packaging ans shipping methods

★ Packaging Form

a. The bulk goods are 20 Kg/Drum or 25 Kg/Drum, the inner is a double plastic bag.

b. The minimum package form is 1 Kg/Aluminum foil bag.

c. The products should be stored in a dry and cool place, keeping away from strong light and heat.

d. The expiration date is 2 years (24 months) when properly stored.

★ Shipping Method

a. Below 50 Kg, we suggest you ship the goods by FEDEX, DHL, UPS, TNT, etc.

b. More than 50 Kg, we suggest you ship the goods by air.

c. Above 500 Kg, we suggest you ship the goods by sea.

 

Our Packaging and Shipping Methods

 

multiple applications

The main product applications of Pineapple Enzyme Bromelain are as below:

 Health Products

a. Dosage Forms: Encapsulated or tablet supplements, often combined with other enzymes.

b. Method of Use: Orally ingested with water, typically before meals to support anti-inflammatory effects or with meals to aid the digestive process.

 Cosmetics

a. Dosage Forms: Incorporated into skin creams, serums, face masks, and exfoliating peels.

b. Method of Use: Applied topically to the skin, where it helps to gently loosen and remove dead skin cells for a smoother texture and clearer appearance.

 Foods

a. Dosage Forms: Used as a processing aid in beverages like protein shakes and smoothies to reduce sediment and improve clarity.

b. Method of Use: Added during the manufacturing process to break down proteins, preventing cloudiness and separation in liquid products.

 Meat Tenderizer

a. Dosage Forms: Available as a powder or within seasoned tenderizing blends.

b. Method of Use: Sprinkled onto the surface of raw meat and allowed to rest. The enzyme breaks down tough muscle fibers and connective tissues, resulting in a more tender texture.

 Animal Feed

a. Dosage Forms: A functional additive in powdered or liquid premixes for feed.

b. Method of Use: Blended into feed formulations to enhance protein digestibility and nutrient absorption, supporting overall digestive well-being in livestock and poultry.

 

our OEM service

At Inhealth Nature, we offer end-to-end OEM solutions for bromelain products, ensuring your brand receives premium formulations tailored to your specifications and market demand. We can provide liquid extracts, capsules, tablets, and topical creams. You can trust us for the following reasons:

 Turnkey Solutions: From raw materials to finished products

 Flexible MOQs: Small batches for startups to bulk production

 Certified Quality: ISO, FSSC, Kosher, and Halal options available

 Market-Ready: Fast formulation for trending niches (dietary supplements, nutraceuticals, cosmetics, foods, and so on)

The following is the process of our OEM service:

 

OEM Service Flow Chart

 

FAQ

Q1: How Do I Take Bromelain Powder?

A: Dosage: There is no single official dosage, as it depends on the purpose. Common supplemental doses range from 250 mg to 1,000 mg per day, often split into 2-3 doses. Timing is Key: a. For Digestive Aid: Take with meals. This directs the enzymes to help digest your food. b. For Anti-inflammatory Effects: Take on an empty stomach (at least 30 minutes before or 1.5 hours after a meal). This allows the enzymes to be absorbed into the bloodstream to exert systemic effects.

Q2: Are There Any Side Effects?

A: Bromelain is generally safe for most people but can cause minor side effects in some: 1)Digestive Upset: Mild diarrhea, stomach cramps, or nausea. 2)Allergic Reactions: More common in individuals allergic to pineapple, latex, carrot, celery, fennel, rye flour, or wheat. Symptoms can include itching, rash, or swelling. 3)Heavy Menstrual Bleeding: It may increase menstrual flow in some women.

Q3: Why is Bromelain Sometimes Listed as a Potential Allergen for People with Wheat or Celery Allergy?

A: This is due to cross-reactivity. The protein structure in bromelain can be similar enough to allergens in pineapple, latex, pollen, celery, and wheat that the immune system of a sensitized individual might mistakenly identify it as a threat, triggering an allergic reaction.

Q4: What Are the Important Drug Interactions?

A: Bromelain can interact with: a.Blood Thinners (e.g., Warfarin, Aspirin, Clopidogrel): Bromelain itself has mild blood-thinning properties. Combining them can increase the risk of bleeding and bruising. b.Antibiotics (e.g., Amoxicillin, Tetracycline): Bromelain may increase the absorption of certain antibiotics, which can be beneficial but should only be done under medical supervision. c.Sedatives: Bromelain may enhance the effects of sedative medications. Always consult your doctor before taking bromelain if you are on any medication.

Q5: Who Should Avoid Bromelain?

A: The following people should avoid bromelain: 1)People with Pineapple or Latex Allergies. Individuals with Bleeding Disorders or those scheduled for surgery (discontinue use at least 2 weeks prior). 2)Pregnant or Breastfeeding Women: Due to a lack of safety data, it's best to avoid it. 3)People with Kidney or Liver Disease.

Q6: How Should I Store Bromelain Powder?

A: Store it in a cool, dark, and dry place, away from heat, light, and moisture. A tightly sealed container in a cupboard is ideal. Proper storage preserves its enzymatic potency.

Q7: Can I Take Bromelain Powder with Other Supplements?

A: Yes, it is often combined with other natural anti-inflammatories like turmeric (curcumin) and ginger, as they can have a synergistic effect. However, because all three can also have mild blood-thinning properties, you must be extra cautious and consult a doctor before combining them, especially if you are on medication.

If you are interested in our pineapple bromelain and other products, please contact us at kathy@inhealthnature.com at your convenience.

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